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In the management of acute and chronic stroke, smartphone apps enhance communication between first responders and waiting hospital staff and reduce door-to-needle time, according to a literature review (Journal of Stroke. Published online Sept. 30, 2022.)

In a new review (Neurobiol Dis. 2022 Oct 15; 105897. doi: 10.1016/j.nbd.2022.105897) the authors explore the effect of gut microbiota manipulation as a therapeutic strategy in epilepsy and the methodological challenges to design (translational) clinical trial investigating the gut microbiota

A weighted blanket of approximately 12% body weight used at bedtime prompted the release of higher concentrations of melatonin, as measured in the saliva, compared with a lighter blanket of only about 2.4% of body weight in a new study.

The factor that is most relevant and strongly associated with the clinical course of multiple sclerosis is chronological age. Very young patients almost exclusively have relapsing remitting disease, whereas those with later onset disease face a more rapid development of permanent disability.