Prostate Medications Linked to Lower Risk of Lewy Body Dementia

01/07/2024

Certain medications used to treat benign prostatic hyperplasia (BPH) may reduce the risk of developing dementia with Lewy bodies (DLB), the second most common neurodegenerative dementia after Alzheimer's. 

Researchers found that older men taking alpha-1 blockers like terazosin, doxazosin, or alfuzosin were 40% less likely to develop DLB compared to those taking tamsulosin and 37% less likely than those on 5-alpha reductase inhibitors (5ARI) like finasteride.

This study, published in Neurology, highlights the potential of existing drugs to offer protection against DLB.